Before polymers, alloys and composites, the wood of Guaiacum officinale, also known as tree of life, was extremely important due to its combination of strength, toughness and density. The common name, Lignum vitae (tree of life or wood of life), comes from its historic medicinal use as a remedy for conditions from arthritis to coughs to syphilis. These uses caused over harvesting, reducing native populations to the point that Lignum vitae is now listed as "Endangered" by IUCN (The World Conservation Union). It is native to most of the Caribbean (including Key West), a 'biodiversity hotspot' that supports exceptionally diverse ecosystems. Most of its native habitat has been devastated by deforestation and development.